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Cancers (Basel) 14:312

Sossen, B., Kubjane, M

NETosis proceeds by cytoskeleton and endomembrane disassembly and PAD4-mediated chromatin decondensation and nuclear envelope rupture

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These factors may lead to hyperactive neurological responses, releasing a cascade of signals that alter cerebral blood vessel dynamics and neurotransmitter levels, such as serotonin and CGRP, leading to the inflammation and pain characteristic of a migraine