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These stubborn areas are characterized by several factors including high alpha-2 adrenergic receptor density relative to beta receptors, reduced blood flow, and greater insulin sensitivity leading to efficient fat storage

Because YAP1 and the transcriptional coactivator with PDZ-binding motif (TAZ, a homologue to YAP1) cannot bind to the DNA directly, they must interact with DNA-binding TFs

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183 HSP70B promotes breast cancer metastasis by upregulating mesenchymal markers such as N-cadherin, MMP2, SNAIL, and vimentin, facilitating EMT