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For patients losing significant weight on compounded semaglutide or tirzepatide, topical GHK-Cu is sometimes used to support skin elasticity, though specific evidence in this population is limited

TB-500 Cell Migration and Regeneration TB-500 promotes cell migration to damaged areas, allowing new healthy tissue to form faster

Apply topically to affected area as directed

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For most people, the relevant answer is about topical timing

Tirzepatide also produces significant insulin sensitivity improvements, outperforming semaglutide in head-to-head diabetes trials