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One mechanistic avenue suggested by Fu et al

The powder may have degraded before reconstitution due to improper storage, high temperature exposure, or moisture infiltration into the sealed vial

In some trials, complete closure was observed in over 95% of wounds by day 15 under GHK-Cu treatment

That said: Skin irritation: Some people experience mild scalp irritation, especially with higher-concentration formulations or poorly formulated vehicles

They encourage the production of collagen and elastin, helping the skin stay firm and healthy

Purity below 95% indicates significant contamination and should be avoided for research use