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Discard if the solution becomes cloudy, develops particulates, or smells off

Some individuals especially those sensitive to changes in methylation activity describe feeling overstimulated or jittery with high-dose methyl B12

Interstitial Cystitis Study (2024): A preliminary trial in 12 patients with interstitial cystitis (a chronic bladder condition) reported resolution of symptoms in 80 - 100% of participants following BPC-157 treatment

Consider periodic monitoring of B12 in patients on metformin with risk factors for B12 deficiency Risk factors are quite wide-ranging and include the following (MHRA, 2022): Baseline vitamin B12 levels at the lower end of the normal range

This makes it a poor medication as you would have to take it every 20 minutes to maintain its levels in the blood

Failing to consume adequate amounts of protein after bariatric surgery can lead to poor muscle health, leaving patients at risk of not being able to maintain appropriate amounts of muscle