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In the brain, magnesium functions as a voltage dependent antagonist and a noncompetitive inhibitor of the N-methyl-D- aspartic acid (NMDA) receptors and ion channels

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Regional Disciplinary Medical Board: vitamin B12 cannot be overdosed In 2009, the Regional Disciplinary Medical Board in Eindhoven stated very clearly that an overdose is not possible: There can be no question of an overdose of hydroxocobalamin, as the excess is excreted in urine by the kidneys and therefore cannot accumulate in the body

Proc Natl Acad Sci USA 87(17):67586761 Kujawski M et al (2008) Stat3 mediates myeloid cell-dependent tumor angiogenesis in mice

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doi:10.1111/acel.13773 15