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Tissue-specific regulation of iron metabolism and heme synthesis: distinct control mechanisms in erythroid cells

PMC 3306410

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Moreover, FSHD was frequently associated with extramuscular involvements, encompassing hearing loss (40%), retinal abnormalities (37%) and developmental delay (8%) showing a negative correlation between D4Z4 repeat size and disease severity, which is comparable with adult-onset FSHD (see Genetics)