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Its identity involves both a three-residue peptide and copper coordination

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There are also additional imaging changes in PD patients, which, however, still necessitate further investigation to develop and disseminate sophisticated imaging and analytic methods, as well as to carry out multi-center, large-sample size studies to create novel imaging indicators, so as to validate their clinical relevance

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Goodfellow MJ, Borcar A, Proctor JL, Greco T, Rosenthal RE, Fiskum G: Transcriptional activation of antioxidant gene expression by Nrf2 protects against mitochondrial dysfunction and neuronal death associated with acute and chronic neurodegeneration