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Daily treatment with 10% CBD oil orally for 14 days improved these behavioral parameters and also reduced the post-injury increases of the neurotransmitters, D-aspartate, glutamate, and GABA in the medial prefrontal cortex [54]

In this regard, a key mode of action to explain this relationship is via glucose transporter type 1 (GLUT1) which increases uptake of the oxidized form of ascorbic acid, dehydroascorbate and subsequently depletes glutathione (Yun et al., 2015)