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doi: 10.1136/bjo.86.12.1369

Funding The fund for this research work was provided by the grant from Indian Council of Medical Research (ICMR F.No

One of the key mechanisms through which nicotinamide may exert these protective effects is by restoring the levels of nicotinamide adenine dinucleotide (NAD+), which is critical for mitochondrial metabolism and energy production

Drug Investig

Mande SS, Sarfaty S, Allen MD, Perham RN, Hol WG (1996) Proteinprotein interactions in the pyruvate dehydrogenase multienzyme complex: dihydrolipoamide dehydrogenase complexed with the binding domain of dihydrolipoamide acetyltransferase

37 reported decreased k cat app and increased K m app (GSSCys) values upon replacement of Lys19 in a single cysteine mutant of human Grx1