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Among older adults (50+), interest in carnitine is linked to its potential role in age-related fatigue and heart health, supported by NIHs Office of Dietary Supplements (ODS), which notes carnitine may benefit individuals with cardiovascular conditions

Similarly, Attia et al

23 Statement #1: strong recommendation, low quality evidence (1C) Any individual at any age who presents with any of the following symptoms should undergo prompt plasma ammonia determination: Acute unexplained encephalopathy Acute neurological illness Suspected sepsis in a newborn Developmental delay of unknown cause Recurrent vomiting Acute liver failure, elevated transaminases of unknown cause Ataxia Headache, especially if episodic in women Coma or stupor Psychiatric symptoms Aversion to protein

Think about the example mentioned earlier relating to autism and carnitine deficiencies: the outcome of something like a gut infection or antibiotic use, can alter intestinal bacterial populations (in this case, increased propionic acid causing a carnitine deficiency)