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Botch is a -glutamyl cyclotransferase that deglycinates and antagonizes Notch

Zhou Z, Hong EJ, Cohen S, Zhao WN, Ho HY, Schmidt L et al (2006)

Scarborough, J

Bioresour Technol Rep 25:101789 Borowitzka MA (2018) Biology of microalgae

Yes, IV administration of vitamin C can provide significantly higher peak plasma concentrations because it bypasses the regulated intestinal uptake of oral vitamin C