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The present analysis reveals that GNPs have the capability to deliver drugs towards the novel intracellular regions and antibodies which are used as a therapeutic agent to treat skin cancer and other diseases, including Rosacea [386]

Disclosures: Breianna Hummer-Bair: Nothing to Disclose, Nataliya Smith: Nothing to Disclose, James Heinle: Nothing to Disclose, Kyra VanKirk: Nothing to Disclose, Kara DiJoseph: Nothing to Disclose, Zeba Hussaini: Nothing to Disclose, Ryan Jackson: Nothing to Disclose, Ian Schreibman: Nothing to Disclose, Elizabeth Stonesifer: Nothing to Disclose, Justin Tondt: Nothing to Disclose, Rohit Loomba: Eli Lilly and Company: Consultant, Kathryn Schmitz: Nothing to Disclose, Scot Kimball: Nothing to Disclose, Jonathan Stine: Zydus Therapeutics: Grant/Research Support, Novo Nordisk: Consultant, Galectin: Grant/Research Support, Novo Nordisk: Grant/Research Support, Astra Zeneca: Grant/Research Support, Noom: Grant/Research Support, Zydus: Grant/Research Support, Kowa: Grant/Research Support 2586 THE IMPACT OF POMEGRANATE CONSUMPTION ON CLINICAL PARAMETERS IN MASLD: A META-ANALYSIS AND A SYSTEMATIC REVIEW Islam Mohamed 1 Hazem Abosheaishaa 2 Sarah George 1 Mira Bhatia 1 Lauren Baetje 1 Suman Manek 1 Nina Henry 1 Khushi Parekh 1 Yazan Abboud 3 Ahmed Salem 4 Fouad Jaber 1 Dushant Dahiya 5 Nikki Duong 6 , 1 University of Missouri - Kansas City, 2 Icahn School of Medicine at Mount Sinai, 3 Rutgers New Jersey Medical School, 4 Maimonides Medical Center, 5 University of Kansas School of Medicine, 6 Stanford University Background: Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) is a significant health concern given its increasing worldwide prevalence

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The product can lower the circulating level of this specific tumor marker and restrain distant metastasis by selectively inhibiting NNMT enzymatic activity, providing valuable new directions for early clinical diagnosis and targeted metastasis intervention

Then, plasmids of wild type Sat1, mutant Sat1 and over-expression of Sox2 were constructed