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Even though this effect may be mediated by the insulin receptor, experimental KO mice for the insulin receptor gene show a potent glucose lowering effect of IGF-1, indicative that the hypoglycaemic effect is also mediated, in part, by its own IGF-1R

This conventional antibody was developed by selecting a precise CD38 sequence and identifying unique complementary-determining regions, which provided much higher sensitivity and improved performance compared to traditional reagents