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Backlogs, staffing limits at state disability offices, and added evidence at this stage can all extend the review

These tend to be mild and resolve as the body adapts

NIH National Library of Medicine (PMC)

Community experience does document common side effects including injection site reactions, occasional headaches, and digestive changes

Common Side Effects When side effects occurred, they were typically mild, transient, and similar in frequency to placebo groups: Reported Adverse Effects Most Common (occurring in small percentage of participants): Mild to moderate headaches (most frequently reported, often resolving with continued use) Injection site reactions (minor redness, swelling, or irritation at injection site) Gastrointestinal effects (particularly at higher oral doses: mild nausea, diarrhea, flatulence) Fatigue (reported occasionally during initial adaptation period) Rare Events: One case of chest tightness was deemed possibly related to treatment in safety trials

Different trials have projected completion dates ranging from 2025 to 2027