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This reduces the permeability of the BBB, preventing harmful substances from entering the brain, improving microvascular stability, and alleviating the pathological changes of epilepsy and other brain diseases

References of the 447 selected articles Additional file 3: Additional Table 2

The role of hypoxia-inducible factor 1-alpha (HIF-1a) in this context is particularly noteworthy

[4] People with conditions that irritate mucosal lining in the stomach and intestines, such as Crohns or celiac disease, [7] chronic alcoholism, or inflammatory bowel disease

Efficacy and Safety by Cytogenetic Risk Status: Phase 3 Study (ASPIRE) of