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(2009) reviewed glutathiones role as the master intracellular antioxidant, describing its enzymatic recycling, compartmentalization, and signaling functions

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Ide T, Tsutsui H, Kinugawa S, Utsumi H, Kang D, Hattori N, Uchida K, Arimura K, Egashira K, Takeshita A (1999) Mitochondrial electron transport complex I is a potential source of oxygen free radicals in the failing myocardium

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14 Complications include iron overload, pulmonary hypertension, endocrinopathies, osteoporosis and bone fractures, extramedullary hematopoiesis, gallstones, and lower extremity ulcers, among others