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Metformin can reduce the vacuolated PTECs, dilated tubules, collagen deposition, and mitochondrial morphological abnormalities to protect PTECs from the impact of FA/IRI by activating the AMPK pathway and promoting the SENP1-SIRT3 axis in FA/IRI-induced AKI mice model

Endocr Rev 26:944984

Enhances Mood and Mental Health: B12 plays a role in synthesizing neurotransmitters, which can improve mood and reduce symptoms of depression and anxiety

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Do proton pump inhibitors affect vitamin B12 absorption

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