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Following blocking with 5% nonfat dry milk in TBST buffer (0.01 m Tris-HCl, pH 8.0, 0.15 m NaCl, and 0.1% Tween 20), membranes were immunoblotted with different primary antibodies

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Organisms possess intricate regulatory mechanisms to ensure the selective degradation of proteins, thereby maintaining protein homeostasis

Small-molecule PIK-93 modulates the tumor microenvironment to improve immune checkpoint blockade response