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PAD-exposed tau inclusions colocalize with AD-associated phospho-tau species To further characterize the pathological tau species formed in the treated MAPT-KI hippocampal neurons, we assessed multiple phospho-tau antibodies for their colocalization with PAD-exposed tau

Determination of maximal power output at neuromuscular fatigue threshold

for MetS and T2D), and because exercise is one of the most potent IGF-1 synthesis/freeing mechanisms, it seems logical to correlate them and establish IGF-1 as a target for future options in the multifactorial treatment for metabolic syndrome

Assessment at the single-cell level identifies neuronal glutathione depletion as both a cause and effect of ischemia-reperfusion oxidative stress

they create what researchers refer to as a massive immunological "energy sink." Because the immune cells (particularly T-cells and memory lymphocytes) are trapped in a state of severe oxidative stress, they are forced to consume excessive amounts of the host's energy just to survive the ongoing cellular damage and attempt repairs

[PubMed] Wannamethee SG, Lennon L, Shaper AG