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Additionally, pseudotime analysis verified that these changes influenced CD4 T cell maturation (Trajectory A) and proliferation (Trajectory B) without elevating inflammatory responses

The etiologies of POF are heterogeneous and multifactorial, and traditional therapies have limited effectiveness, benefiting only a small proportion of patients

Wang et al., 2020

UMMC 2014a

Combinations of Treatment Methods As GLP-1 RA and amylin analog-induced weight loss arise from both distinct and overlapping mechanisms, the combination of GLP-1 RA and amylin RA has been shown to produce a synergistic effect [118]