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This review highlights that given the robust preclinical evidence and high public interest, there is a critical need for well-designed human trials to assess the safety, efficacy, and clinical utility of BPC-157 in musculoskeletal medicine

Blood was collected via jugular vein catheters, centrifuged to obtain serum, and stored at -20C

Trial-product estimand

However, individual tolerance varies

Because Dihexa promotes structural changes in synaptic density and neural connections, effects often persist beyond treatment duration, allowing for cycling approaches rather than continuous use

Zero placebo-controlled human studies of dihexa have been published