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501 Activation of Nrf2 prevents ferroptosis by upregulating ferritin, SLC7A11 and GPX4

Methyl indole -3-carboxylate (Standard) is an analytical standard of Methyl indole -3-carboxylate (HY-79635)

It was more effectively activated by elevated levels of GSH in H1299 lung cancer cells than that in normal lung fibroblasts WI38 cells, releasing reactive alkoxyamines to capture AP sites, blocking APE1 repair, and leading to lung cancer cell death in vitro

Characteristics : More common in men, this type can also affect the chin, forehead, cheeks, and ears

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