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Int J Behav Dev 2005;29:46878

Gene therapy for cancer: present status and future perspective

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Sn phm s dng cng ngh chit xut protein hin i - Hybrid-Ratio Ion-Filtration (HRI)

Rather than binding to His residues with a very low K D in A42, Cu 2+ bound to a high- K D , low-affinity site, i.e., Met, coupled to an oxidation-reduction one-electron transfer from the Met S-atom to the Cu(II) ion, is consonant with the mechanism of forming a sulfuranyl free radical on the Met35 residue posited by the Butterfield laboratory as key to initiating lipid peroxidation in AD as described above