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Selective Bcl-xL inhibitors include a vaccine for prostate cancer and ABBV-155, an antibody-drug conjugate being studied as monotherapy or for use in combination with taxanes for solid tumors (Walensky et al., 2004)

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CagriSema adds the amylin pathway on top of GLP-1: cagrilintide engages amylin/calcitonin receptors, a mechanism entirely absent from tirzepatide

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Wnt/-catenin signalling pathway has shown strong immunosuppressive function in a variety of tumours, and potentially become a novel target of tumour treatment