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It inhibits the release of an antidiuretic hormone, leading to increased urine production and dehydration

Similar to our results, Edin et al

Wright CJ, Rentschler KM, Wagner NT, Lewis AM, Beggiato S, Pocivavsek A (2021) Time of day-dependent alterations in hippocampal kynurenic acid, glutamate, and GABA in adult rats exposed to elevated kynurenic acid during neurodevelopment

Sequencing data from the CRISPR screens are available in the Gene Expression Omnibus (accession number GSE268182)

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