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57 This triggers the transcription of genes encoding antioxidants such as SOD, catalase, GSH, glutathione reductase (GR), GSH S-transferase (GSTP), GPX, TRXR, NADPH quinone oxidoreductase 1 (NQO1), and heme oxygenase-1 (HO-1), which neutralize ROS and protect cells against oxidative stress, especially in conditions such as cancer, where ROS levels are elevated 57 (Fig

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One of the holy grails of the cancer field is understanding how the tumor suppressor protein TP53 works to inhibit tumor initiation

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Another bonus of a glutathione IV: Side effects are minimal