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Conclusion: Evidence-Based Sourcing of GHK-Cu Skin UK for Research Applications GHK-Cu represents a well-characterized, gene-regulatory tripeptide with documented effects on collagen synthesis, MMP inhibition, and antioxidant enzyme expression

and regulation of gene expression via interaction with transcription factors such as STAT3 and Nrf2 24

Finally, the L protein catalyzes the re-oxidation of the lipoyl moiety of the H protein in an NAD + -dependent reaction, generating NADH and a proton (H + )

In contrast, the KA + XMU-MP-1 mice did not increase GFAP expressions in CA1 astrocytes and the expression level of GS was as same as Saline + DMSO mice (Fig