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The above may provide a mechanistic rational to its potential clinical cardiovascular protection effects

doi: 10.1096/fj.202400088R, PMID: [DOI] [PubMed] [Google Scholar] 41

Thus, they may also have a role in chronic kidney disease

Nitric oxide bioavailability dysfunction involves in atherosclerosis

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We fused the Flag sequence (DYKDDDDK) and cell-penetrating peptide sequence TAT (CYGRKKRRQRRR) to each of the upper CXCL10 regions and named them CIBB-1 (CXCL10IL18R1 binding blocker 1) and CIBB-2 (CXCL10IL18R1 binding blocker 2) (Fig