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J Am Chem Soc 144:701708 Her J, Zheng H, Bunting SF (2024) RNF4 sustains Myc-driven tumorigenesis by facilitating DNA replication

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As limitaes atuais da pesquisa incluem a ausncia de ensaios clnicos randomizados de grande porte em humanos, uma compreenso ainda parcial dos mecanismos moleculares precisos e uma carncia de dados farmacocinticos detalhados em humanos