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Nat Commun (2016) 7:10274

Improved gout outcomes in primary care using a novel disease management program: a pilot study

These data suggest that a common stress-related ancestor with a Trx-like fold may have pre-dated the evolution of the thiol-oxidase function now most commonly associated with the Trx-like fold

ergothioneine an antioxidant and anti-inflammatory present throughout the body, is obtainable solely through food, with mushrooms being the most concentrated source by far