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Together, these results support that DMF activates the TSS pathway and thus contributes to the regulation of cellular oxidative and ferroptosis stress response

On the other hand, the RCT design with evaluation of multiple objectively measured outcomes (dynamometry, algometry, TSAII) increases the methodological quality of the study

However, ferroptotic damage may also promote chronic inflammation and create a tumor-permissive microenvironment, depending on the genetic and immune status of the tissue

Villani RG, Gannon J, Self M, Rich PA

Epigenetic mechanisms in neurological disease

Data Availability Statement Data availability is not applicable to this review as no new data were created or analyzed in this study