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Orthogonal least squares discriminant analysis (OPLS-DA) was then used for classification discrimination to obtain variable importance (VIP) in projections of metabolites

Individual PD patients do not often show easily detectable grey matter loss at diagnosis, although at group level, PD patients show cortical thinning and reduced subcortical and cerebellar volume compared to controls 119,120

However, these proportions shifted towards the control distribution following L-serine administration (Supplementary Fig

[32] However, in more complex situations, such as nerves being damaged by severe B12 deficiency, full recovery can sometimes take up to a year

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