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Furthermore, overexpression of JMJD2A leads to a decrease in H3K36 methylation, reducing HR repair efficiency, which may weaken the radiation resistance of tumors

Christen and Fent 2017)

Editor TurksenK., 3746

Dendrimer-based systems, particularly polyamidoamine (PAMAM) dendrimers, enable high drug-loading capacity and facilitate nuclear targeting in cancer cells [20]

Peptides degrade faster in warm environments, and the 60 mg vial is too expensive to treat casually

HMG-CoA reductase degradation protein 1 (Hrd1) mediates the efflux of misfolded proteins from the endoplasmic reticulum [28], and together with suppressor/Enhancer of lin-12-like (Sel1l) forms the Sel1l-Hrd1 complex, which identifies and degrades misfolded proteins within the ER [29]