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The metabolism of the gut microbiome can also modulate antibiotic efficiency, as noted in high-fat diet-fed mice, such that the tryptophan metabolite indole-3-acetic acid promotes antibiotic efficacy against persisters 53

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As such, while preclinical evidence supports the hypothesis that exercise can regulate oxidative stress and HPA axis function, the extent to which these findings can be generalized to human populations is still waiting to be investigated

e7 (2017)

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