foxo4-dri senolytic 2023 2024 study induces keloid senescent fibroblast apoptosis by promoting nuclear exclusion of upregulated p53-serine 15 phosphorylation FOXO4-DRI improves spermatogenesis in aged
FOXO4 DRI improves spermatogenesis in aged mice through reducing senescence associated secretory phenotype secretion from Leydig cells ScienceDirect Senolytics: charting a new course or enhancing existing anti tumor therapies? Cellular Oncology Springer Nature Link The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4 DRI Nature Communications Molecular modelling of the FOXO4 TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells ScienceDirect ES2 rapidly destroys TP53 FOXO4 foci leading to TP53 mediated Download Scientific Diagram FOXO4 an overview ScienceDirect Topics
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