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This has been tentatively associated with various metabolic consequences

Although not evaluated here, lower intracellular GSH levels would also deactivate the GSH-dependent GPX4, further enhancing ferroptotic cell death (8, 38)

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NK cells were co-cultured with Mtb-infected MDMs and treated with the indicated inhibitors in the presence of anti-LILRB1 (GHI/75) mAb or IgG control for 24 h

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This conjugation process transforms lipophilic toxins into water-soluble glutathione adducts that can be efficiently eliminated through bile or urine