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Category 2 includes substances that raise significant safety or efficacy concerns, meaning they generally cannot be used in compounding unless specific criteria are met

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Amin N, Wu F, Zhao B-X, Shi Z, Abdelsadik A, Elshazly Younis A, Naz Abbasi I, Sundus J, Badry Hussein A, Geng Y (2025) Hif-1 ablation reduces the efficiency of NeuroD1 gene-based therapy and aggravates the brain damage following ischemic stroke

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