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Glutamine is first transported into the cell and then into the inner mitochondrial membrane via specific transporters before being converted into glutamate by mitochondrial glutaminase

Reactive or rosacea-prone skin

Dull or uneven body skin

6, E and F)

Importantly, several studies describing anti-ferroptotic activity are based mainly on general reductions in ROS or oxidative stress markers, while ferroptosis-specific confirmation requires assessment of key indicators such as GPX4 regulation, glutathione depletion, lipid peroxidation products, and iron-dependent rescue experiments [94, 95]

Data demonstrated that the inhibitor ML385 alone did not significantly affect cell viability but significantly inhibited the protein expression of p-Nrf2 (Fig