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Reports from pharmacologically induced PD models using the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) demonstrate that specific mitochondrial toxins inhibit complex I (CI) activity, thereby promoting degeneration of dopaminergic neurons within the substantia nigra 29

Physiol Rev 88:611638

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Galasso et al., 2018), and even anti-ferroptosis properties in several diseases, which are different to those of vitamin E (Kong et al., 2023

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