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Moreover, SLE patients showed increased ROS production and enhanced catalase activity in neutrophils

b , View of the FIX Prop-Glu model with VKGC shown in electrostatic surface

Ethics declarations Competing interest The authors declare that there are no conflicts of interest

Surprisingly, these animals do not show multiorgan autoimmunity, but develop an AIH-1 like disease, with interface hepatitis, positive ANA and anti-SLA antibodies, suggesting that intact central tolerance is key to prevent AIH-1 [118]