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These findings suggest that the role of glia, at least microglia, in axon regeneration is complex, and it is oversimplistic to classify their behavior as binary: beneficial or inhibitory

In 2023, Seorin Juhng et al

It has been shown that while proinflammatory cytokines such as TNF- and IL-1 increase the expression of GR, the formation of the GR/ heterodimer attenuates the function of GR 14 (Figure 1)