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Fan W, Evans RM

Further research is needed to optimize Exos-based therapies and translate these insights into clinical applications

The translocation of nuclear-encoded DNMT1 into the mitochondria matrix is guided by a conserved mitochondrial targeting sequence, and its activity has been shown to influence transcription from both heavy and light mtDNA strands [35] (Fig

Methods Mol Biol 494:18

Bielefeldt K, Levinthal DJ, Nusrat S

In renal tissue, acute or chronic systemic injections of trimetazidine have been shown to reduce thiobarbituric acid reactive substances in immunosuppressant-induced renal dysfunction [178] and prevent SOD, glutathione peroxidase, catalase or glutathione decrease in ischemia/reperfusion injury in rats [179, 180]