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In addition, changes in metabolic pathways further regulates the phenotype and function of immune cells, thereby affecting the bodys immune response

This finding underscores KDM5C s role in ID and suggests that gene-specific methylation patterns may directly influence ID phenotypes, highlighting the value of identifying methylation signatures to better understand genetic contributions to ID severity

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Irritable Bowel Syndrome and Other Intestinal Disorders Irritable bowel syndrome (IBS) is a functional digestive disorder characterized by frequent abdominal pain related to shifts in the frequency and formation of bowel actions [44]

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242 PKC activation enhances excitatory currents in the dorsal horn and trigeminal neurons, contributing to nociceptive hypersensitivity in DPN