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Different peptides target different aspects of this triad, and understanding which does what is essential for designing effective peptide approaches

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The data in Figure 24 confirm this expectation by demonstrating that D-Nle-Cys-Ile-NH-(CH 2 )5-CONH 2 and D-Nle-Tyr-Ile-NH-(CH 2 ) 5 -CONH 2 , which bind HGF with high affinity (Figure 23) and effectively attenuate HGF-dependent processes (Figures 25, 26, 27 ) completely block HGF dimer formation

Registered Phase 1 Study ClinicalTrials.gov contains a Phase 1 record registered under NCT02637284