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10.1111/jcmm.14936 76 LuZ.ZhangG.ZhangY.HuaP.FangM.WuM.et al (2018)

Shimadzu Corp., Kyoto, Japan)

Decades of genome-wide linkage scans have confirmed that PSORS1 is the most significant susceptibility locus identified through familial linkage studies, accounting for up to 50% of the genetic contribution to psoriasis (Rahman and Elder 2005)