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Correlation between two groups was evaluated by the Pearsons test

The data revealed that higher Notch1 level coincided with higher MANF level, while lower Notch1 level accompanied by lower MANF level in ICC cell lines (Supplementary Fig

Figure 2 Changing dietary intake from organic healthy foods to highly processed foods may lead to increased exposure to advanced glycated end products aged garlic extracts (AGEs) by a non-enzymatic chemical reaction called glycation ( Different Researches explain that older individuals have been exposed to both endogenous and exogenous AGE (34)

Following the generation of large amounts of ROS, necroptosis is activated