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Expiration date applies to manufactured drugs based on FDA-required stability testing

A lack of vitamin B12 can cause health problems like fatigue and a type of anemia called megaloblastic anemia, where the body makes unhealthy red blood cells that cant carry enough oxygen

If you develop severe allergic reactions such as difficulty breathing, facial swelling, or widespread rash after a B12 injection, call 999 or go to A&E immediately, as these may indicate anaphylaxis, though this is extremely rare

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Comment: One commenter stated that if the surgeon did not report modifier -54, the claim from a different physician or practice during the 90-day global period is denied as bundled unless it is an unrelated E/M service

Phase II Clinical Trials These promising preclinical findings led to Phase I and Phase II clinical trials in humans