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Both untargeted (LCMS) and targeted (GCMS) metabolomics approaches were used to assess serum profiles

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Dualities of AR expression and activity in cancer Melanoma is a key example where AR has dual functions depending on its basal versus upregulated expression and activity

FAO, fatty acid oxidation

7-Hydroxycoumarin (7-HC) can alleviate renal tubule expansion, epithelial cell detachment, and necrosis in the colistin-induced kidney injury mice model and the mice RTECs treated with colistin, and this protective effect is achieved by reducing the level of HDAC1, activating the Nrf2 signaling pathway to upregulate the protein expressions of Nrf2, HO-1, and H3K27AC, thereby enhancing the kidneys antioxidant capacity

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