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Description

They used random mutagenesis to generate over 3,500 individual IL-1a mutants that averaged 2.5 amino acid changes per variant over the entire length of the molecule

Gressler S, Hipfinger C, Part F, Pavlicek A, Zafiu C, Giese B

ALA has also been observed to enhance insulin-stimulated glucose uptake in skeletal muscle, thereby improving insulin sensitivity in patients with type 2 diabetes